Thyroid MCQs
1. propylthiouracil has a longer half-life
than carbimazole.
2. carbimazole
and propylthiouracil act to block thyroid hormone synthesis by inhibiting thyroid peroxidase.
3.It is
prudent to have a white cell count (WCC) during any febrile illness for all
patients taking antithyroid medication.
4.life-threatening
agranulocytosis, which is defined as a neutrophil count of less than 0.05x109/L.
5. Cluster
of symptoms and signs of agranulocytosis includes mouth ulcers, sore throat, fever,
and rash.
Answers
1. FALSE-Carbimazole has longer half-life so prescribed
one or twice daily but PTU three times daily.
2. TRUE-Mechanism of action
3. FALSE -Need a differential WCC (Febrile neutropenia
has serious consequences)
4. TRUE-
5. TRUE-Need patient education preferably written
instruction to stop the antithyroid medications immediately.
