ANDROGEN DEFICIENCY IN MALE

Symptoms and signs suggestive of
androgen deficiency in men

• Incomplete sexual development, eunuchoidism,
aspermia
• Reduced sexual desire (libido) and activity
• Decreased spontaneous erections
• Breast discomfort, gynecomastia
• Loss of body (axillary and pubic) hair, reduced shaving
• Very small or shrinking testes (especially < 5 mL)
• Inability to father children, low or zero sperm counts
• Height loss, low-trauma fracture, low bone mineral
density
• Reduced muscle bulk and strength
• Hot flushes, sweats

AUTOSOMAL DOMINENT CONDITIONS

Autosomal dominant inheritance is seen in:


Achondroplasia, Acute intermittent porphyria, Adult polycystic kidney disease, Ehlers-Danlos syndrome, Familial adenomatous polyposis, Gilbert's syndrome, Hereditary sensory and motor neuropathy, Hereditary spherocytosis, Huntington's disease, Hyperlipidaemia type II, Malignant hyperthermia, Marfan's syndrome, Myotonia congenita, Myotonic dystrophy, Neurofibromatosis, Osteogenesis imperfecta type 1, Noonan's syndrome, Polyposis coli, Rotor syndrome, Retinoblastoma, Tuberose sclerosis, Von Hippel-Lindau disease, von Willebrand's disease