MUSCULAR DYSTROPHY

SPINAL MUSCULAR DYSTROPHY -MCQS
RED FLAGS SIGNS OF SPINAL MUSCULAR DYSTROPHY INCLUDES

1.Hypotonia.
2.No head control.
3.Absent reflexes.
4.Tounge fasciculation.
5.Cognitive impairment.

ANSWERS
1.TRUE-Profound hypotonia
2.TRUE-Little or no head control
3.TRUE-Absent ,reduced or asymmetric moro reflex and deep tendon reflexes
4.TRUE-feeding difficulty, recurrent respiratory tract infections.
5.FALSE-Normal cognitive development(baby is happy and bright but lazy!)

Rheumatic Fever

HEUMATIC FEVER -MCQS

1.One of the complications of GAS(Group A streptococcus)infection
2.Immune mediated complication that can affect Heart ,Skin, Brain, Joints
3.Cardiac complications may be long lasting.
4.Recurrent episodes of rheumatic fever is unlikely after initial episode.
5.Considering the risk category the diagnostic criteria may be different.


Answers
1. TRUE-a Non suppurative complications
2. TRUE-Heart-carditis, Skin-osler’s nodes/Janeway lesions, Brain -retinal roth spots,Joints -arthralgia
3. TRUE-May be life long
4. FLASE-depends on individual risk
5. TRUE

PCOS-polycystic ovarian syndrome

POLYCYSTIC OVARIAN SYNDROME -MCQS

 

1.    Can be diagnosed without USS(Ultra sound scan )of both ovaries.

2.    Can affect anyone assigned/presumed female at birth.

3.    Primary amenorrhoea is one of the  diagnostic criteria.

4.    Insulin resistance is an associated metabolic disorder.

5.    Androgenetic alopecia is a consequence of excess ovarian androgen production

 

ANSWERS

1.TRUE-with menstrual disturbance and clinical or biochemical hyperandrogenism (a diagnosis of exclusion)

2.TRUE-

3.FALSE-secondary amenorrhoea

4.TRUE-

5.TRUE-

DRUG INDUCED THYROIDITIS

DRUG INDUCED THYROIDITIS-MCQS

 

1.Tyrosine kinase inhibitors are associated with thyroid dysfunction.

2.Alemtuzumab(Lemtrada) is associated with thyroid dysfunction.

3.Immune checkpoint inhibitors are associated with thyroid dysfunction.

4.Amiodarone contains about 68% by weight of iodine.

5.Lithium associated thyroid dysfunction is commonly seen few weeks after commencing treatment.

 

 

ANSWERS

1.    TRUE-

2.    TRUE-used to treat multiple sclerosis

3.    TRUE-are monoclonal antibodies

4.    TRUE

5.    FALSE-generally occurring after 8-12 months of treatment.

EUTHYROID HYPERTHYROXINAEMIA

EUTHYROID HYPETHYROXINAEMIA-MCQ

1. Seen in amiodarone associated thyroid dysfunction.
2. Total T3 and /or T4 may be elevated
3. fT4/fT3 levels are normal.
4. TSH levels are normal
5. In clinical practice the commonest cause is due to a congenital or acquired alteration in thyroid binding proteins.


ANSWERS
1. TRUE-other associated dysfunctions include hyperthyroidism and hypothyroidism
2. TRUE-
3. TRUE-
4. TRUE-today serum TSH is a screening test for thyroid function, and a normal TSH value should not be followed by measurement of total T4.
5. TRUE-Thyroxine binding globulin(TBG),Thyroxine binding pre-albumin(TBPA) and Albumin.