PCOS-polycystic ovarian syndrome

POLYCYSTIC OVARIAN SYNDROME -MCQS

 

1.    Can be diagnosed without USS(Ultra sound scan )of both ovaries.

2.    Can affect anyone assigned/presumed female at birth.

3.    Primary amenorrhoea is one of the  diagnostic criteria.

4.    Insulin resistance is an associated metabolic disorder.

5.    Androgenetic alopecia is a consequence of excess ovarian androgen production

 

ANSWERS

1.TRUE-with menstrual disturbance and clinical or biochemical hyperandrogenism (a diagnosis of exclusion)

2.TRUE-

3.FALSE-secondary amenorrhoea

4.TRUE-

5.TRUE-

DRUG INDUCED THYROIDITIS

DRUG INDUCED THYROIDITIS-MCQS

 

1.Tyrosine kinase inhibitors are associated with thyroid dysfunction.

2.Alemtuzumab(Lemtrada) is associated with thyroid dysfunction.

3.Immune checkpoint inhibitors are associated with thyroid dysfunction.

4.Amiodarone contains about 68% by weight of iodine.

5.Lithium associated thyroid dysfunction is commonly seen few weeks after commencing treatment.

 

 

ANSWERS

1.    TRUE-

2.    TRUE-used to treat multiple sclerosis

3.    TRUE-are monoclonal antibodies

4.    TRUE

5.    FALSE-generally occurring after 8-12 months of treatment.

EUTHYROID HYPERTHYROXINAEMIA

EUTHYROID HYPETHYROXINAEMIA-MCQ

1. Seen in amiodarone associated thyroid dysfunction.
2. Total T3 and /or T4 may be elevated
3. fT4/fT3 levels are normal.
4. TSH levels are normal
5. In clinical practice the commonest cause is due to a congenital or acquired alteration in thyroid binding proteins.


ANSWERS
1. TRUE-other associated dysfunctions include hyperthyroidism and hypothyroidism
2. TRUE-
3. TRUE-
4. TRUE-today serum TSH is a screening test for thyroid function, and a normal TSH value should not be followed by measurement of total T4.
5. TRUE-Thyroxine binding globulin(TBG),Thyroxine binding pre-albumin(TBPA) and Albumin.

THYROIDITIS MCQS

De QUERVAIN’S THYROIDITIS -MCQS-2

1.During initial phase of thyrotoxicosis associated high T4:T3 ration suggests release of stored thyroid hormones.
2.ESR is markedly elevated.
3.Treatment is focused around the management of pain and inflammation of the thyroid gland.
4.Anti-thyroid medications are not indicated.
5.Steroids are considered first line therapy.

ANSWERS
1. TRUE-due to release of stored thyroid hormones.
2. TRUE-due to inflammation
3. TRUE
4. TRUE-since the preformed thyroid hormones released to the circulation is responsible for symptoms.
5. FALSE-NSAIDS, and beta blockers for symptom control-steroid are reserved for resistant cases.

HASHIMOTOS THYROIDITIS-MCQS

1. Recurrent postpartum thyroiditis is common in subsequent pregnancies
2. The initial hyperthyroid phase can easily be missed clinically.
3. Hypothyroid state is more commonly seen in clinical practice
4. Hypothyroidism is usually insidious in onset and may be progressing over years.
5. Is the most common cause of hypothyroidism in iodine insufficient areas of the world

ANSWERS
1. TURE-more than 75%
2. TRUE
3. TRUE
4. TRUE-Need monitoring
5. TRUE-

THYROIDITIS

THYROIDITIS -MCQS

1.Results in release of preformed thyroid hormone stores due to thyroid follicular cell destruction.
2. A common cause of thyrotoxicosis.
3.Rdionuclide thyroid scan shows heterogeneous uptake.
4. Can present with or without underlying thyroid disease.
5.De Quervain’s thyroiditis is a painful form of thyroiditis which usually follows a viral infection.

Answers
1. TRUE-follicular cell apoptosis due to inflammation.
2. FALSE- less common but a recognized cause.
3. FALSE-near absent uptake.
4. TRUE
5. TRUE-usually after upper respiratory tract infection-there are characteristic clinical features that needs to be actively sought but diagnosis is often significantly delayed.(history of URTI,firm tender thyroid,neck/jaw /ear pain,persistent sore throat)